Quality requirements
Automated pipette tip inspection
Automated inspection stations from Ziemann & Urban, equipped with industrial cameras from SVS-Vistek and other image processing components, enable pipette tip manufacturers to inspect pipette tips with high precision and cost-effectively.
They are used in medical technology and laboratories worldwide to dispense liquids in precise doses and then examine them: Pipettes. Their tips must meet very strict quality requirements in order to perform their task as desired, as Markus Urban, one of the Managing Directors of Ziemann & Urban from Moosinning in Bavaria, knows: "Even slight burrs in the injection mold or other defects on a pipette tip can lead to liquids not ending up where they should in the laboratory or to incorrect liquid quantities. This can lead to incorrect measurement results, which must be avoided at all costs in medical technology."
The production of such pipette tips, which are usually made of plastic, often takes place in fully automated injection molding processes that run around the clock without a break. The production speeds are so high that a 100% inspection of all manufactured parts would be technically feasible, but not economically justifiable. "As a compromise, we have therefore designed our systems to be so flexible that they can carry out isolated measurements cyclically and, depending on customer requirements, can check a complete tray with high precision once an hour, for example."
The test objects vary considerably depending on the manufacturer and application: The length is usually between 20 and 120 mm, the diameter can vary in the range of 0.5 to 2.5 mm, and transparent or black are most commonly used for the colors. "The effort required to cover this range with automated systems is considerable for a disposable product. However, due to the field of application in the medical sector, we believe it is absolutely necessary in order to realize the inspection of these essential components economically," emphasizes Urban.
Modular solution
The solution that Ziemann & Urban has developed for this challenging task is modular in order to meet the different requirements of pipette tip manufacturers from all over the world. When measuring diameters, burrs and wobble circles, some of their requirements are for accuracies of less than 1 μm, which is why the company relies on high-quality image processing: customers can choose between different versions with two to nine cameras to check the quality features, depending on their requirements. According to Urban, the most common version works with six cameras: "In this configuration, one camera inspects the pipette tips from above, one from below and four from the side, with the lower camera being movable in height to cover different pipette lengths." Optionally, additional cameras can also be used to measure the absolute length of the pipette tips and their wobble circle, including a 3D calculation as a stereo system.
Ziemann & Urban has been relying on industrial cameras from SVS-Vistek's EXO series for several years now. "These cameras have an excellent sensor resolution and a good price-performance ratio for this application. In combination with the perfect housing size and the proven stability of the EXO cameras, we have found the optimal choice for our automatic inspection machines: We use models with GigE Vision interface, resolutions of up to 25 megapixels and C-mount lens connection for the appropriate optics." SVS-Vistek also offers the EXO cameras with USB3 and Camera Link interfaces, M42, MFT mount (Micro Four Thirds) and EF mount adapters as well as resolutions from 1.6 to 31.4 megapixels.
The tight tolerances of the pipette tips require resolutions in the low µm range, which can only be achieved by using high-quality telecentric illumination and optics without perspective distortion. "In this application, we have a relatively small field of view of just 5.8 x 5.8 mm and work with telecentric lenses," says Urban. "By using suitable telecentric illumination, we were able to detect defect sizes down to approx. 1.7 µm and thus clearly meet our customers' requirements."
Successful in use
In Hekuma, Ziemann & Urban has found a sales and automation partner with good market access in the medical industry. Hekutip QC Assistant is the name of the systems that Ziemann & Urban produces for Hekuma and which can be used worldwide.
"The resulting solutions are efficient and, with inspection speeds of five to ten seconds per part, offer a fast inspection process that relieves the burden on measuring laboratories and reduces the need to retain highly qualified personnel for this task," reports Urban.









